Studien und Publikationen
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Publikationen
Transrectal versus transperineal prostate fusion biopsy: a pair-matched analysis to evaluate accuracy and complications.
Oderda M, Diamand R, Abou Zahr R, Anract J, Assenmacher G, Barry Delongchamps N, Bui AP, Benamran D, Calleris G, Dariane C, Ferriero M, Fiard G, Taha F, Fourcade A, Fournier G, Guenzel K, Halinski A, Marra G, Ploussard G, Rysankova K, Roche JB, Simone G, Windisch O, Gontero P.
World J Urol. 2024 Sep 25;42(1):535. doi: 10.1007/s00345-024-05245-1.
Refining clinically relevant cut-offs of prostate specific antigen density for risk stratification in patients with PI-RADS 3 lesions.
Mjaess G, Haddad L, Jabbour T, Baudewyns A, Bourgeno HA, Lefebvre Y, Ferriero M, Simone G, Fourcade A, Fournier G, Oderda M, Gontero P, Bernal-Gomez A, Mastrorosa A, Roche JB, Abou Zahr R, Ploussard G, Fiard G, Halinski A, Rysankova K, Dariane C, Delavar G, Anract J, Barry Delongchamps N, Bui AP, Taha F, Windisch O, Benamran D, Assenmacher G, Benijts J, Guenzel K, Roumeguère T, Peltier A, Diamand R.
Prostate Cancer Prostatic Dis. 2024 Jul 24. doi: 10.1038/s41391-024-00872-6. Online ahead of print.
External validation and comparison of magnetic resonance imaging-based risk prediction models for prostate biopsy stratification.
Diamand R, Guenzel K, Jabbour T, Baudewyns A, Bourgeno HA, Lefebvre Y, Ferriero M, Simone G, Fourcade A, Fournier G, Bui AP, Taha F, Oderda M, Gontero P, Rysankova K, Bernal-Gomez A, Mastrorosa A, Roche JB, Fiard G, Abou Zahr R, Ploussard G, Windisch O, Novello Q, Benamran D, Delavar G, Anract J, Barry Delongchamps N, Halinski A, Dariane C, Vlahopoulos L, Assenmacher G, Roumeguère T, Peltier A.
World J Urol. 2024 Jun 12;42(1):372. doi: 10.1007/s00345-024-05068-0.
The impact of prostate volume estimation on the risk-adapted biopsy decision based on prostate-specific antigen density and magnetic resonance imaging score.
Baudewyns A, Guenzel K, Halinski A, Dariane C, Delavar G, Anract J, Barry Delongchamps N, Jabbour T, Bourgeno HA, Lefebvre Y, Ferriero M, Simone G, Fourcade A, Fournier G, Oderda M, Gontero P, Bernal-Gomez A, Mastrorosa A, Roche JB, Zahr RA, Ploussard G, Fiard G, Rysankova K, Bui AP, Taha F, Windisch O, Benamran D, Vlahopoulos L, Assenmacher G, Roumeguère T, Peltier A, Diamand R.
World J Urol. 2024 May 15;42(1):322. doi: 10.1007/s00345-024-04962-x.
Reduction of false positives using zone-specific prostate-specific antigen density for prostate MRI-based biopsy decision strategies.
Hamm CA, Baumgärtner GL, Padhani AR, Froböse KP, Dräger F, Beetz NL, Savic LJ, Posch H, Lenk J, Schallenberg S, Maxeiner A, Cash H, Günzel K, Hamm B, Asbach P, Penzkofer T.
Eur Radiol. 2024 Oct;34(10):6229-6240. doi: 10.1007/s00330-024-10700-z. Epub 2024 Mar 28.
PMID: 38538841
Transperineal or Transrectal Magnetic Resonance Imaging-targeted Biopsy for Prostate Cancer Detection.
Diamand R, Guenzel K, Mjaess G, Lefebvre Y, Ferriero M, Simone G, Fourcade A, Fournier G, Bui AP, Taha F, Oderda M, Gontero P, Rysankova K, Bernal-Gomez A, Mastrorosa A, Roche JB, Fiard G, Abou Zahr R, Ploussard G, Windisch O, Novello Q, Benamran D, Delavar G, Anract J, Barry Delongchamps N, Halinski A, Dariane C, Benijts J, Assenmacher G, Roumeguère T, Peltier A.
Eur Urol Focus. 2024 Mar 19:S2405-4569(24)00047-6. doi: 10.1016/j.euf.2024.03.003. Online ahead of print.
The Added Value of Side-specific Systematic Biopsy in Patients Diagnosed by Magnetic Resonance Imaging-targeted Prostate Biopsy.
Bourgeno HA, Jabbour T, Baudewyns A, Lefebvre Y, Ferriero M, Simone G, Fourcade A, Fournier G, Oderda M, Gontero P, Bernal-Gomez A, Mastrorosa A, Roche JB, Abou Zahr R, Ploussard G, Fiard G, Halinski A, Rysankova K, Dariane C, Delavar G, Anract J, Barry Delongchamps N, Bui AP, Taha F, Windisch O, Benamran D, Assenmacher G, Vlahopoulos L, Guenzel K, Roumeguère T, Peltier A, Diamand R.
Eur Urol Oncol. 2024 Jan 24:S2588-9311(24)00031-2. doi: 10.1016/j.euo.2024.01.007. Online ahead of print.
Diagnostic Utility of Artificial Intelligence–assisted Transperineal Biopsy Planning in Prostate Cancer Suspected Men: A Prospective Cohort Study
Günzel K, Baumgaertner GL, Padhani AR, Luckau J, Lock UC, Ozimek T, Heinrich S, Schlegel J, Busch J, Magheli A, Struck J, Borgmann H, Penzkofer T, Hamm B, Hinz S, Hamm CA
Eur Urol Focus. 2024 Apr 29:S2405-4569(24)00059-2. doi: 10.1016/j.euf.2024.04.007. Online ahead of print.
Evaluation of systematic prostate biopsies when performing transperineal MRI/TRUS fusion biopsy with needle tracking-what is the additional value?
Günzel K, Magheli A, Busch J, Baco E, Cash H, Heinrich S, Edler D, Schostak M, Borgmann H, Schlegel J, Hinz S.
Int Urol Nephrol. 2022 Jul 25. doi: 10.1007/s11255-022-03309-y.
Antibiotic prophylaxis versus no antibiotic prophylaxis in transperineal prostate biopsies (NORAPP): a randomised, open-label, non-inferiority trial.
Jacewicz M, Günzel K, Rud E, Sandbæk G, Magheli A, Busch J, Hinz S, Baco E.
Lancet Infect Dis. 2022 Jul 12:S1473-3099(22)00373-5. doi: 10.1016/S1473-3099(22)00373-5.
Follow-up of men with a PI-RADS 4/5 lesion after negative MRI/Ultrasound fusion biopsy.
Kornienko K, Reuter M, Maxeiner A, Günzel K, Kittner B, Reimann M, Hofbauer SL, Wiemer LE, Heckmann R, Asbach P, Wendler JJ, Schostak M, Schlomm T, Friedersdorff F, Cash H.
Infection rate and complications after 621 transperineal MRI-TRUS fusion biopsies in local anesthesia without standard antibiotic prophylaxis.
Günzel K, Magheli A, Baco E, Cash H, Heinrich S, Neubert H, Schlegel J, Schostak M, Henkel T, Asbach P, Hinz S.
World J Urol. 2021 Apr 18. doi: 10.1007/s00345-021-03699-1.
Multicenter transperineal MRI-TRUS fusion guided outpatient clinic prostate biopsies under local anesthesia.
Jacewicz M, Günzel K, Rud E, Mæhre Lauritzen P, Flor Galtung K, Hinz S, Magheli A, Baco E.
Urologic Oncology: Seminars and Original Investigations. doi: 10.1016/j.urolonc.2020.11.009. Epub 2020 Nov 27
Initial results of perineal MRI/ultrasound fusion biopsies under local anesthesia without standard perioperative antibiotic prophylaxis
Günzel K, Heinrich S, Schlegel J, Ri C, Schostak M, Magheli A, Shahin O, Hinz S.
Urologe A. 2020 Oct;59(10):1225-1230. doi: 10.1007/s00120-020-01164-2.
Predictive Parameters Identifying Men Eligible for a Sole MRI/Ultrasound Fusion-Guided Targeted Biopsy without an Additional Systematic Biopsy.
Günzel K, Haas M, Maxeiner A, Stephan C, Buckendahl J, Asbach P, Miller K, Kempkensteffen C, Cash H.
Urol Int. 2017;98(1):15-21. doi: 10.1159/000449258. Epub 2016 Sep 13.
The addition of a sagittal image fusion improves the prostate cancer detection in a sensor-based MRI /ultrasound fusion guided targeted biopsy.
Günzel K, Cash H, Buckendahl J, Königbauer M, Asbach P, Haas M, Neymeyer J, Hinz S, Miller K, Kempkensteffen C.
BMC Urol. 2017 Jan 13;17(1):7. doi: 10.1186/s12894-016-0196-9. (geteilte Autorenschaft)
The detection of significant prostate cancer is correlated with the Prostate Imaging Reporting and Data System (PI-RADS) in MRI/transrectal ultrasound fusion biopsy.
Cash H, Maxeiner A, Stephan C, Fischer T, Durmus T, Holzmann J, Asbach P, Haas M, Hinz S, Neymeyer J, Miller K, Günzel K, Kempkensteffen C. 2015b. World journal of urology. (geteilte Autorenschaft)
Is the Ellipsoid Formula the New Standard for 3-Tesla MRI Prostate Volume Calculation without Endorectal Coil?Haas M, Günzel K, Miller K, Hamm B, Cash H, Asbach P.
Urol Int. 2017;98(1):49-53. doi: 10.1159/000448593. Epub 2016 Sep 15.
Implications of PI-RADS Version 1 and Updated Version 2 on the Scoring of Prostatic Lesions in Multiparametric MRI.
Haas M, Günzel K, Penzkofer T, Maxeiner A, Fischer T, Miller K, Hamm B, Asbach P, Cash H.
Aktuelle Urol. 2016 Sep;47(5):383-7. doi: 10.1055/s-0042-111128. Epub 2016 Sep 28.
Prostate cancer detection on transrectal ultrasonography-guided random biopsy despite negative real-time magnetic resonance imaging/ultrasonography fusion-guided targeted biopsy: reasons for targeted biopsy failure.
Cash H, Günzel K, Maxeiner A, Stephan C, Fischer T, Durmus T, Miller K, Asbach P, Haas M, Kempkensteffen C. 2015a.
BJU international.
Real-time MRI/US fusion-guided biopsy in biopsy-naive and pre-biopsied patients with suspicion for prostate cancer
Maxeiner A, Stephan C, Fischer T, Durmus T, Kilic E, Asbach P, Haas M, Günzel K, Neymeyer J, Miller K, Cash H. 2015.
Implications of PI-RADS Version 1 and Updated Version 2 on the Scoring of Prostatic Lesions in Multiparametric MRI.
Haas M, Günzel K, Penzkofer T, Maxeiner A, Fischer T, Miller K, Hamm B, Asbach P, Cash H.
Aktuelle Urol. 2016 Sep;47(5):383-7. doi: 10.1055/s-0042-111128. Epub 2016 Sep 28.
Prostate cancer detection on transrectal ultrasonography-guided random biopsy despite negative real-time magnetic resonance imaging/ultrasonography fusion-guided targeted biopsy: reasons for targeted biopsy failure.
Cash H, Günzel K, Maxeiner A, Stephan C, Fischer T, Durmus T, Miller K, Asbach P, Haas M, Kempkensteffen C. 2015a.
BJU international.
Real-time MRI/US fusion-guided biopsy in biopsy-naive and pre-biopsied patients with suspicion for prostate cancer.
Maxeiner A, Stephan C, Fischer T, Durmus T, Kilic E, Asbach P, Haas M, Günzel K, Neymeyer J, Miller K, Cash H. 2015.
Aktuelle Urologie, 46, 34-8.
Optimum Trial
Diese Studie schließt Patienten mit dem Verdacht auf ein Prostatakarzinom vor einer Prostatabiopsie ein. Mit der Studie soll die diagnostische Genauigkeit des hochauflösenden transrektalen (durch den Darm) Ultraschall (ExactVuTM) im Vergleich zur multiparametrischen Magnet-Resonanz-Tomographie (mpMRT) verglichen werden. Patienten werden nach dem Zufall (Randomisierung) in 3 Gruppen (Prostatabiopsie mit ExactVuTM, MRT/Ultraschall-Fusionsbiopsie, Prostatabiopsie mit MRT und ExactVuTM) eingeteilt. Ihr Vorteil ist, dass bei der Prostatabiopsie ein bildgebendes Verfahren (ExactVuTM oder mpMRT) angewendet wird, dass die Detektionsgenauigkeit für ein Prostatakarzinom deutlich erhöht.
Patienteneinschluss ist abgeschlossen